Why the study?
Does depression affect in-hospital mortality and adverse effects in hospitalized patients with ESRD on hemodialysis?
Population
Hospitalized patients with end-stage renal disease on hemodialysis from the National Inpatient Sample.
Comparison
Depression (as a comorbidity) vs No depression
Design
Cohort
Follow-up
In-hospital
Key result
Among hospitalized hemodialysis patients, depression was associated with a decreased risk of in-hospital mortality but an increased rate of adverse effects in discharged patients.
Authors
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Depression-linked lower in-hospital mortality in hemodialysis patients should not change practice; leaves open confounding and post-discharge risks for prospective study.
Observational
Yes
Does depression affect in-hospital mortality and adverse effects in hospitalized patients with ESRD on hemodialysis?
In hospitalized hemodialysis patients, depression is associated with a paradoxical decrease in in-hospital mortality but an increase in adverse effects post-discharge.
Chan et al. (2017) conducted an observational in End-stage renal disease on hemodialysis. Depression vs. No depression was evaluated on In-hospital mortality. Among hospitalized hemodialysis patients, depression was associated with a decreased risk of in-hospital mortality but an increased rate of adverse effects in discharged patients.