Key result
Trypanosomatids possess a large number of unique RNA-binding proteins that act as trans-acting factors to regulate the expression of co-regulated mRNA cohorts.
This review highlights the role of unique RNA-binding proteins in post-transcriptional gene regulation in trypanosomatids.
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May guide target identification in trypanosomatid gene regulation; leaves open therapeutic translation to Chagas cardiomyopathy.
Krämer et al. (2010) conducted a review in Trypanosomatid gene expression. Trypanosomatids possess a large number of unique RNA-binding proteins that act as trans-acting factors to regulate the expression of co-regulated mRNA cohorts.
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