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Treatment of 3,4-epoxy-6-substitutedhex-5-yn-1-ols with BF3·OEt2 gave the endo-mode cyclization products with inversion of stereochemistry, whereas conversion of the epoxides to the corresponding hexacarbonyldicobalt complexes, followed by Lewis-acid treatment provided the endo-mode products with retention of configuration at the newly formed stereogenic centre.
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Mukai et al. (1994) studied this question.
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