Key result
Partial left ventriculectomy decreased end-systolic volume more than end-diastolic volume, improving stroke volumes and doubling ejection fraction at 180 days follow-up.
Why the study?
Does partial left ventriculectomy improve angiographic and hemodynamic parameters in patients?
Observational (n=24)
Does partial left ventriculectomy improve angiographic and hemodynamic parameters in patients?
Partial left ventriculectomy improves systolic contractility and ejection fraction, with success appearing to depend on myocardial viability and improved diastolic relaxation.
Angiographic, Doppler-echocardiographic and hemodynamic studies early (+6 days) and late (+180 days) after partial left ventriculectomy (PLV) on 24 patients revealed that PLV decreased end-systolic volume (or dimension) more than the end-diastolic volume (or dimension), improving stroke volumes (or contractile excursion), and doubling ejection fraction (or fractional shortening). Results of PLV appeared to depend on a balance between improved systolic contractility and reduced diastolic performance. All these survivors had improved diastolic relaxation, suggesting myocardial viability is a prerequisite for PLV to be successful.
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Kawaguchi et al. (2005) conducted an observational in Patients after partial left ventriculectomy (n=24). Partial left ventriculectomy (PLV) was evaluated on Angiographic, Doppler-echocardiographic and hemodynamic parameters. Partial left ventriculectomy decreased end-systolic volume more than end-diastolic volume, improving stroke volumes and doubling ejection fraction at 180 days follow-up.
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