Key result
A pregnant patient with mechanical aortic and mitral valve prostheses who developed heparin-induced thrombocytopenia at term was managed perioperatively with fondaparinux.
Why the study?
Does fondaparinux safely manage heparin-induced thrombocytopenia perioperatively in a pregnant patient with mechanical heart valves?
Case Report (n=1)
Does fondaparinux safely manage heparin-induced thrombocytopenia perioperatively in a pregnant patient with mechanical heart valves?
Fondaparinux can be used for the perioperative management of heparin-induced thrombocytopenia in pregnant patients with mechanical heart valves.
Patients with prosthetic heart valves are at higher risk of thromboembolism and need anticoagulation prophylaxis. Pregnancy poses higher risk for the same and heparins can be used safely in these patients however there are many side effects of heparin therapy including heparin induced thrombocytopenia (HIT). Pregnancy with prosthetic valves developing HIT has never been reported. We report a case of one such patient who had a mechanical aortic and mitral valve prosthesis who developed HIT at term pregnancy and was managed perioperatively with fondaparinux.
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Yaqoob et al. (2014) conducted a case report in Heparin induced thrombocytopenia in pregnancy with mechanical heart valves (n=1). Fondaparinux was evaluated on Perioperative management of heparin induced thrombocytopenia. A pregnant patient with mechanical aortic and mitral valve prostheses who developed heparin-induced thrombocytopenia at term was managed perioperatively with fondaparinux.
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