Key result
Pregnancy in heart transplant and LVAD recipients is associated with increased risks of graft rejection, preeclampsia, thromboembolic events, and right ventricular failure.
Why the study?
Women of reproductive age are increasingly undergoing HT or LVAD implantation for advanced heart failure, necessitating an overview of current state-of-the-art pregnancy management in this population.
Pregnancy in women with LVADs or heart transplants is high-risk and requires preconception counseling and close multidisciplinary surveillance.
Supports multidisciplinary preconception counseling in these patients; leaves open prospective registries to guide management.
PURPOSE OF REVIEW: Women of reproductive age are increasingly undergoing heart transplantation (HT) or left ventricular assist device (LVAD) implantation for advanced heart failure. This review is intended to give an overview of the current state of the art management of pregnancy in patients with LVAD or HT recipients. RECENT FINDINGS: Heart transplant recipients are at increased risk for graft rejection, renal dysfunction, preeclampsia and worsening of comorbidities (hypertension and diabetes). Patients with LVAD are at higher risk of thromboembolic events, infections, right ventricular failure and require close surveillance during pregnancy. Preconception counseling must be offered to all women of reproductive age group with HT or LVAD to avoid unplanned pregnancies. SUMMARY: A multidisciplinary approach with close antepartum and postpartum surveillance is recommended.
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Marek‐Iannucci et al. (2023) conducted a review in Pregnancy in heart transplant or LVAD recipients. Pregnancy was evaluated. Pregnancy in heart transplant and LVAD recipients is associated with increased risks of graft rejection, preeclampsia, thromboembolic events, and right ventricular failure.
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