Key result
Elevated symptoms of depression were not associated with increased IL-6 or TNFalpha cytokine levels in patients with chronic renal failure (p=0.937 and p=0.414, respectively).
Why the study?
Are elevated symptoms of depression associated with increased proinflammatory cytokine levels in patients with chronic renal failure?
Population
93 patients with chronic renal failure
Design
Cross-sectional
Authors
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No association between depressive symptoms and IL-6/TNFα in chronic renal failure; hypothesis-generating and requires prospective confirmation before clinical consideration.
Cross-Sectional (n=93)
Are elevated symptoms of depression associated with increased proinflammatory cytokine levels in patients with chronic renal failure?
p-value: p=0.937 and 0.414
In patients with chronic renal failure, elevated depressive symptoms are not associated with increased levels of proinflammatory cytokines IL-6 and TNFalpha.
Dervişoğlu et al. (2008) conducted a cross-sectional in Chronic renal failure (n=93). Elevated symptoms of depression vs. Without elevated symptoms of depression was evaluated on IL-6 and TNFalpha cytokine levels (p=0.937 and 0.414). Elevated symptoms of depression were not associated with increased IL-6 or TNFalpha cytokine levels in patients with chronic renal failure (p=0.937 and p=0.414, respectively).
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