Key result
Intravenous infusion of isoproterenol in healthy men consistently decreased transmural right atrial pressure by an average of 1.9 mm Hg and reduced forearm venous distensibility.
Why the study?
Does isoproterenol infusion alter peripheral venous tone and transmural right atrial pressure in healthy men?
Does isoproterenol infusion alter peripheral venous tone and transmural right atrial pressure in healthy men?
Isoproterenol infusion in healthy men causes peripheral venous constriction and decreases transmural right atrial pressure, suggesting a central shift of blood that may contribute to increased cardiac output.
Answers are grounded in this paper and cite their sources.
Venous effects in healthy men do not support clinical practice changes; leaves open contribution to cardiac output in disease.
edge no observations on the peripheral venous re
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Eckstein et al. (1959) studied Healthy (n=10). Isoproterenol vs. Pre-infusion control period was evaluated on Transmural right atrial pressure (mean decrease 1.9 mm Hg, p=<0.02). Intravenous infusion of isoproterenol in healthy men consistently decreased transmural right atrial pressure by an average of 1.9 mm Hg and reduced forearm venous distensibility.
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