Key result
Intravenous practolol successfully controlled severe tachyarrhythmia following a severe imipramine overdose in a pediatric patient.
Why the study?
Does intravenous practolol control severe tachyarrhythmia in a pediatric patient with imipramine overdose?
Does intravenous practolol control severe tachyarrhythmia in a pediatric patient with imipramine overdose?
Intravenous practolol successfully controlled severe tachyarrhythmia in a pediatric case of imipramine overdose, suggesting its potential utility in this specific toxicological emergency.
Answers are grounded in this paper and cite their sources.
May support practolol consideration in pediatric imipramine overdose; hypothesis-generating case report leaves efficacy unconfirmed.
A 2½-year-old boy, comatose and having fits after an overdose of imipramine, suffered a respiratory and cardiac arrest from which he was successfully resuscitated. A severe tachyarrhythmia was well controlled by intravenous practolol, and it is suggested that practolol is the drug of choice in this situation.
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Brown et al. (1972) studied this question. Intravenous practolol successfully controlled severe tachyarrhythmia following a severe imipramine overdose in a pediatric patient.
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