What does this research mean for the field?

Institutional racism and racial bias negatively impact the clinical management of sickle cell disease, leading to less favorable clinical prognoses and higher rates of depression among affected patients. Novelty: ClaimNovelty.SYNTHESIS. Consensus alignment: ConsensusAlignment.NEUTRAL.

What question did this study set out to answer?

To assess how racial discrimination and institutional bias affect the healthcare experiences, clinical management, and health outcomes of patients with sickle cell disease.

September 8, 2026Hematology Transfusion and Cell TherapyOpen Access

Racial discrimination and healthcare disparities in sickle cell disease: An integrative review

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Authors

RSRui Santos ACAndré Peres Barbosa Castro WRWaldecy Rodrigues

Discussion

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Overview

Integrative review reveals systemic racial discrimination worsens clinical management and mental health in sickle cell disease, highlighting the urgent need for equitable healthcare policies.

Key Points

To assess how racial discrimination and institutional bias affect the healthcare experiences, clinical management, and health outcomes of patients with sickle cell disease.
Conducted an integrative literature review evaluating racial disparities and clinical prognoses in sickle cell disease.
Identified and synthesized evidence from 11 published articles addressing socioeconomic vulnerability, systemic racism, and healthcare outcomes.
Institutional racism and provider bias contribute directly to poorer clinical prognoses and elevated rates of depression among Black patients with sickle cell disease.
Racial biases among healthcare professionals negatively alter their perception and clinical approach to managing acute sickle cell complications.

Cite This Study

Santos et al. (2026) studied this question.

synapsesocial.com/papers/6a9fd75858e84d0ff5b45e7a https://doi.org/10.1016/j.htct.2026.106529

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September 8, 2026Hematology Transfusion and Cell TherapyOpen Access

Racial discrimination and healthcare disparities in sickle cell disease: An integrative review

View Full Paper

Ask AI

Bookmark

Authors

RSRui Santos ACAndré Peres Barbosa Castro WRWaldecy Rodrigues

Discussion

Member takes

Overview

Integrative review reveals systemic racial discrimination worsens clinical management and mental health in sickle cell disease, highlighting the urgent need for equitable healthcare policies.

Key Points

To assess how racial discrimination and institutional bias affect the healthcare experiences, clinical management, and health outcomes of patients with sickle cell disease.
Conducted an integrative literature review evaluating racial disparities and clinical prognoses in sickle cell disease.
Identified and synthesized evidence from 11 published articles addressing socioeconomic vulnerability, systemic racism, and healthcare outcomes.
Institutional racism and provider bias contribute directly to poorer clinical prognoses and elevated rates of depression among Black patients with sickle cell disease.
Racial biases among healthcare professionals negatively alter their perception and clinical approach to managing acute sickle cell complications.

Cite This Study

Santos et al. (2026) studied this question.

synapsesocial.com/papers/6a9fd75858e84d0ff5b45e7a https://doi.org/10.1016/j.htct.2026.106529

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