Key result
Cyclic fluctuations of arterial pH in dogs coincided with respiratory rate, with the magnitude of fluctuation increasing as respiratory frequency decreased.
Why the study?
Does varying respiratory rate and depth affect the cyclic fluctuation of arterial pH in dogs?
Population
Dogs under sodium pentobarbital anesthesia
Comparison
Varying rates and depths of respiration… vs Baseline/control respiration
Design
Preclinical
Authors
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May influence arterial blood gas timing at varying respiratory rates; leaves open translation to human physiology or practice.
Does varying respiratory rate and depth affect the cyclic fluctuation of arterial pH in dogs?
In a canine model, arterial pH fluctuates cyclically with respiration, with the amplitude of fluctuation increasing at lower respiratory frequencies and decreasing with deeper breathing.
Honda et al. (1961) studied this question. Varying rates and depths of respiration vs. Baseline or different respiratory rates was evaluated on Cyclic fluctuation of arterial pH. Cyclic fluctuations of arterial pH in dogs coincided with respiratory rate, with the magnitude of fluctuation increasing as respiratory frequency decreased.
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