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October 30, 2009Clinical Rehabilitation

Long-term myocardial adaptations after cardiac rehabilitation in heart failure: a randomized six-year evaluation using magnetic resonance imaging

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Why the study?

Does a one-month intensive residential rehabilitation programme improve long-term exercise capacity and left ventricular function in patients with chronic heart failure?

Population

16 patients with chronic heart failure who were alive and available for evaluation after six years

Comparison

One month of intensive residential… vs Usual care

Design

RCT, Randomized

Follow-up

6 years

Key result

A one-month residential rehabilitation program for chronic heart failure increased peak VO2 by 12.4% at 6 years compared to minimal changes in controls, with preserved ventricular function.

Authors

LMLionel MüllerJMJonathan MyersWKWilhard Kottman

Discussion

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Overview

Supports brief residential rehab for durable exercise capacity gains in chronic HF; extends short-term RCT evidence to 6-year durability.

Study Design

Type

RCT (n=50)

Randomization

randomized

Multicenter

Yes

Structured PICO

Does a one-month intensive residential rehabilitation programme improve long-term exercise capacity and left ventricular function in patients with chronic heart failure?

P
Population
50 patients with chronic heart failure randomized to a one-month residential rehabilitation program or usual care, with 16 patients evaluated at 6-year follow-up.
I
Intervention
One month of intensive residential rehabilitation including educational sessions, a low-fat diet, and 2 hours of individually prescribed exercise daily
C
Comparator
Usual care
O
Outcome
Cardiopulmonary exercise test responses and ventricular size and function using MRIsurrogate

A one-month intensive residential rehabilitation program in heart failure patients preserves exercise capacity and may prevent adverse ventricular remodeling at six years.

Cite This Study

Müller et al. (2009) conducted an RCT in chronic heart failure (n=50). Residential rehabilitation programme vs. Usual care was evaluated on Cardiopulmonary exercise test responses and ventricular size and function using MRI. A one-month residential rehabilitation program for chronic heart failure increased peak VO2 by 12.4% at 6 years compared to minimal changes in controls, with preserved ventricular function.

synapsesocial.com/papers/6aa014f0d40bd26775e61ea5https://doi.org/10.1177/0269215509339003
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Exercise capacity, physical activity patterns and outcomes six years after cardiac rehabilitation in patients with heart failure2007 · 62 citations
  2. 2Long-term Effects of Cardiac Rehabilitation and the Paradigms of Cardiac Rehabilitation2005 · 10 citations
  3. 3Effect of Exercise Training on Myocardial Remodeling in Patients With Reduced Left Ventricular Function After Myocardial Infarction1997 · 172 citations
  4. 4Maintenance of Exercise Capacity and Physical Activity Patterns 2 Years After Cardiac Rehabilitation2005 · 58 citations
  5. 5Long-Term Exercise Maintenance, Physical Activity, and Health-Related Quality of Life After Cardiac Rehabilitation2004 · 71 citations