Key result
Propafenone showed good efficacy for atrio-ventricular re-entry tachycardia (80%), atrial flutter (71%) and atrial ectopic tachycardia (83%), but was poor in ventricular arrhythmias (40%).
Population
72 children with cardiac arrhythmias, mean age 34 months.
Design
Case_series
Authors
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May support propafenone for pediatric supraventricular arrhythmias; hypothesis-generating and should not change practice without prospective data.
Observational (n=72)
Propafenone is effective for treating supraventricular arrhythmias in children, particularly those with normal hearts or early after congenital heart surgery, but shows poor efficacy for ventricular arrhythmias.
Heusch et al. (1994) conducted an observational in Cardiac arrhythmias (n=72). Propafenone was evaluated on Efficacy of oral treatment. Propafenone showed good efficacy for atrio-ventricular re-entry tachycardia (80%), atrial flutter (71%) and atrial ectopic tachycardia (83%), but was poor in ventricular arrhythmias (40%).
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