Case Report (n=1)
No
Amiodarone can cause multiorgan toxicity and keratopathy even at low doses (200 mg/day) and relatively short treatment periods (8 months).
Even low-dose amiodarone may cause multiorgan toxicity; this case report leaves open prospective incidence estimates.
Amiodarone is an antiarrhythmic medication that can adversely effect various organs including lungs, thyroid gland, liver, eyes, skin, and nerves. The risk of adverse effects increases with high doses and prolonged use. We report a 54-year-old female who presented with multiorgan toxicity after 8 months of low dose (200 mg/day) amiodarone treatment. The findings of confocal microscopy due to amiodarone-induced keratopathy are described. Amiodarone may cause multiorgan toxicity even at lower doses and for shorter treatment periods.
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Tunçer et al. (2015) conducted a case report in Paroxysmal atrial fibrillation (n=1). Amiodarone was evaluated on Multiorgan toxicity (hypothyroidism, skin discoloration, hepatotoxicity, and corneal vortex keratopathy).
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