Key result
Bypass surgery plus medical treatment significantly improved subjective quality of life at 3 months compared to medical therapy alone (79.8% vs 58.0%, p<0.01) in patients with unstable angina.
Why the study?
Does bypass surgery plus medical treatment improve quality of life in patients with unstable angina compared to medical treatment alone?
Population
468 patients with unstable angina
Comparison
Bypass surgery plus medical treatment vs Medical treatment alone
Design
RCT, randomized
Follow-up
5 years
Authors
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Supports bypass surgery plus medical therapy for early QoL gains in unstable angina; confirms primary RCT benefit on patient-reported outcomes.
RCT (n=468)
randomized
Yes
Does bypass surgery plus medical treatment improve quality of life in patients with unstable angina compared to medical treatment alone?
Absolute Event Rate: 79.8% vs 58%
p-value: p=<0.01
In patients with unstable angina, bypass surgery combined with medical therapy provides significant and sustained improvements in quality of life, chest pain status, and exercise capacity compared to medical therapy alone.
Booth et al. (1991) conducted an RCT in unstable angina (n=468). Bypass surgery plus medical treatment vs. Medical treatment was evaluated on Subjective improvement at 3 months (p=<0.01). Bypass surgery plus medical treatment significantly improved subjective quality of life at 3 months compared to medical therapy alone (79.8% vs 58.0%, p<0.01) in patients with unstable angina.
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