Key result
Oral propafenone administration in a man with a history of malignant ventricular arrhythmias resulted in incessant ventricular tachycardia and subsequent death within several hours.
Population
1 man with a past history of malignant ventricular arrhythmias occurring late after myocardial infarction…
Design
Case_report
Follow-up
Several hours
Authors
Loading...
Alerts clinicians to possible fatal proarrhythmia with propafenone in patients with malignant ventricular arrhythmias; single case leaves open population-level risk.
Case Report (n=1)
Propafenone, a class IC antiarrhythmic agent, can have severe proarrhythmic effects leading to fatal ventricular tachycardia in patients with prior myocardial infarction and ventricular arrhythmias.
Nathan et al. (1984) conducted a case report in Malignant ventricular arrhythmias late after myocardial infarction (n=1). Oral propafenone was evaluated on Incessant ventricular tachycardia and death. Oral propafenone administration in a man with a history of malignant ventricular arrhythmias resulted in incessant ventricular tachycardia and subsequent death within several hours.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: