Key result
Circulatory units at the capillary level in the rat heart result in the temporary persistence of anoxic areas during recovery from anoxia, which are compromised during high heartbeat rates.
Heterogeneity in myocardial hypoxia during recovery or high demand is determined by circulatory units at the capillary level.
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Rat capillary units may prolong anoxic zones during anoxia recovery at high rates; hypothesis-generating for human myocardial hypoxia heterogeneity.
İnce et al. (1993) studied Hypoxia in rat hearts. Ischemic and high-flow anoxia, microsphere embolization, high heartbeat rates vs. Normoxic recovery, low beat rates, presence of adenosine was evaluated on Heterogeneity in hypoxic state (NADH fluorescence and PO2 distribution). Circulatory units at the capillary level in the rat heart result in the temporary persistence of anoxic areas during recovery from anoxia, which are compromised during high heartbeat rates.
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