Why the study?
Stroke prevention is paramount in AF, but patients unable to tolerate oral anticoagulants require alternative non-pharmacological approaches such as percutaneous or surgical LAA closure.
Design
Review
Key result
Left atrial appendage closure, including recent surgical and percutaneous devices, provides a feasible treatment alternative for stroke prevention in non-valvular atrial fibrillation patients with contraindications to oral anticoagulants.
Authors
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May support LAA strategies in anticoagulant-intolerant AF; hypothesis-generating and requires prospective validation before practice change.
Surgical LAAC via thoracoscopy is emerging as a feasible, less invasive alternative to percutaneous LAAC for stroke prevention in non-valvular AF patients with NOAC failure or high bleeding risk.
Dong Seop Jeong (2023) conducted a review in Atrial fibrillation. Left atrial appendage closure vs. Oral anticoagulants was evaluated. Left atrial appendage closure, including recent surgical and percutaneous devices, provides a feasible treatment alternative for stroke prevention in non-valvular atrial fibrillation patients with contraindications to oral anticoagulants.
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