Key result
Sequence analysis of rinderpest virus isolates revealed distinct geographic lineages in Africa and Asia, with no correlation found between cleavage site amino acid changes and pathogenicity.
Population
Rinderpest virus isolates from Africa and Asia
Design
Preclinical
Authors
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Animal study data on rinderpest require validation before extrapolation; leaves open molecular drivers of pathogenicity.
Sequence analysis of rinderpest virus isolates reveals distinct geographic lineages but no correlation between cleavage site amino acid changes and pathogenicity.
Chamberlain et al. (1993) studied Rinderpest virus. Sequence analysis of fusion protein gene was evaluated on Lineage and sequence similarity of rinderpest virus isolates. Sequence analysis of rinderpest virus isolates revealed distinct geographic lineages in Africa and Asia, with no correlation found between cleavage site amino acid changes and pathogenicity.
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