Key result
Persistent iatrogenic atrial septal defect occurred in 28% of patients 12 months after percutaneous mitral valve repair and was associated with increased rehospitalization (RR 9.52; p=0.004).
Why the study?
Risk factors influencing iatrogenic atrial septal defect persistence and its functional consequences following percutaneous mitral valve repair are not fully understood.
What is the prevalence and clinical impact of persistent iatrogenic atrial septal defect following percutaneous mitral valve repair?
Meta-Analysis (n=361)
What is the prevalence and clinical impact of persistent iatrogenic atrial septal defect following percutaneous mitral valve repair?
Relative Risk: 9.52
p-value: p=0.004
Persistent iatrogenic atrial septal defect occurs in 28% of patients 12 months after percutaneous mitral valve repair and is associated with right heart volume overload and increased rehospitalization.
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Persistent iASD after PMVR was associated with right heart overload and rehospitalization; leaves open whether closure alters outcomes in observational data.
Maier et al. (2021) conducted a meta-analysis in Percutaneous mitral valve repair (n=361). Persistent iatrogenic atrial septal defect (iASD) vs. No iASD persistence was evaluated on Rehospitalization (RR 9.52, p=0.004). Persistent iatrogenic atrial septal defect occurred in 28% of patients 12 months after percutaneous mitral valve repair and was associated with increased rehospitalization (RR 9.52; p=0.004).
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