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December 1, 2009Pediatrics & NeonatologyOpen Access

Peritoneal Dialysis in Infants and Children After Open Heart Surgery

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Key result

Delayed initiation of peritoneal dialysis (4.3 vs 1.2 days, P=0.001) and longer cardiopulmonary bypass time (154 vs 111 minutes, P=0.012) were associated with mortality in pediatric patients with ARF.

Why the study?

What are the risk factors for mortality in pediatric patients requiring peritoneal dialysis for acute renal failure after open heart surgery?

Population

542 children who underwent open heart surgery for congenital heart disease, of which 15 developed acute…

Design

Cohort

Authors

JCJen-Chung ChienBHBe‐Tau HwangZWZen-Chung Weng

Discussion

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Overview

May signal higher mortality with delayed peritoneal dialysis in pediatric post-surgical ARF; leaves open whether earlier initiation improves outcomes in prospective trials.

Study Design

Type

Cohort (n=542)

Structured PICO

What are the risk factors for mortality in pediatric patients requiring peritoneal dialysis for acute renal failure after open heart surgery?

P
Population
542 infants and children who underwent open heart surgery for congenital heart disease, of whom 7 required peritoneal dialysis for acute renal failure.
E
Exposure
Peritoneal dialysis (PD) for acute renal failure
O
Outcome
Mortality and risk factors associated with prolonged peritoneal dialysishard clinical

Early initiation of peritoneal dialysis in pediatric patients developing acute renal failure after open heart surgery is associated with improved survival.

Cite This Study

Chien et al. (2009) conducted a cohort in Acute renal failure after open heart surgery (n=542). Risk factors for mortality (cardiopulmonary bypass time, timing of PD) vs. Survivors was evaluated on Risk factors associated with mortality. Delayed initiation of peritoneal dialysis (4.3 vs 1.2 days, P=0.001) and longer cardiopulmonary bypass time (154 vs 111 minutes, P=0.012) were associated with mortality in pediatric patients with ARF.

synapsesocial.com/papers/6aa0e31db6e053eb128d3612https://doi.org/10.1016/s1875-9572(09)60077-2
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Also Consider

Synapse has enriched one closely related paper. Consider it for comparative context:

  1. 1Risks of acute renal failure after cardiopulmonary bypass surgery in children: a retrospective 10-year case-control study1995 · 101 citations