Key result
Percutaneous leaflet repair with MitraClip in inoperable patients with severe mitral regurgitation and cardiogenic shock resulted in a 72.7% 30-day survival free of significant MR.
Why the study?
Severe mitral regurgitation complicated by cardiogenic shock carries high operative mortality, and the effectiveness and safety of percutaneous leaflet repair with MitraClip were unknown.
Does percutaneous leaflet repair with MitraClip improve 30-day survival free of significant MR in inoperable patients with severe mitral regurgitation complicated by cardiogenic shock?
Population
11 inoperable patients with severe MR and cardiogenic shock
Comparison
Percutaneous leaflet repair with MitraClip without a comparator
Design
Single-center retrospective study
Follow-up
1 year
Authors
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MitraClip achieved short-term MR control in select inoperable shock cases; leaves open comparative effectiveness versus alternatives.
Observational (n=11)
No
Does percutaneous leaflet repair with MitraClip improve 30-day survival free of significant MR in inoperable patients with severe mitral regurgitation complicated by cardiogenic shock?
Percutaneous mitral valve repair with MitraClip offers a feasible short-term therapeutic option for highly vulnerable, inoperable patients presenting with severe MR and cardiogenic shock.
García et al. (2020) conducted an observational in Severe mitral regurgitation complicated by cardiogenic shock (n=11). Percutaneous leaflet repair with MitraClip was evaluated on 30-day survival free of significant MR (grade ≤2). Percutaneous leaflet repair with MitraClip in inoperable patients with severe mitral regurgitation and cardiogenic shock resulted in a 72.7% 30-day survival free of significant MR.
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