Key result
Psoriasis linked to ~5 ms longer inter-atrial electromechanical delay and increased P-wave dispersion versus controls.
Why the study?
Do patients with psoriasis have prolonged atrial electromechanical delay and P-wave dispersion compared to healthy controls?
Case-Control (n=64)
Do patients with psoriasis have prolonged atrial electromechanical delay and P-wave dispersion compared to healthy controls?
Absolute Event Rate: 28% vs 23%
p-value: p=0.002
Patients with psoriasis have prolonged atrial electromechanical delay and P-wave dispersion, which may indicate an increased risk of atrial fibrillation.
Prolonged atrial conduction in psoriasis may signal elevated AF risk; leaves open whether these markers predict clinical arrhythmias.
BACKGROUND: In this study, we sought to evaluate atrial electromechanical properties and conduction homogeneity by tissue Doppler imaging and electrocardiography in patients with psoriasis. METHODS: Thirty-four patients with psoriasis and 30 age- and gender-matched healthy controls were included in the study. Atrial electromechanical coupling intervals were assessed by means of tissue Doppler echocardiography and P-wave dispersion (Pd) was calculated from electrocardiogram. RESULTS: A total of 64 subjects (33 male) with a mean age of 36.8 ± 11.9 years were included in the study. Basal characteristics were similar between 2 groups. Intra-atrial (15 ± 7 ms vs. 12 ± 5 ms, P = 0.009) and inter-atrial (28 ± 7 ms vs. 23 ± 7 ms, P = 0.002) electromechanical delays were significantly higher in patients with psoriasis compared with control groups. P-maximum (112 ± 16 ms vs. 103 ± 8 ms, P = 0.006) and Pd (35 ± 9 ms vs. 20 ± 6 ms, P < 0.001) were also prolonged in patients with psoriasis. CONCLUSION: This study demonstrated that atrial electromechanical coupling intervals and P-wave dispersion were prolonged in patients with psoriasis, which may cause an increased risk of atrial fibrillation in this patient group.
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Yıldız et al. (2014) conducted a case-control in Psoriasis (n=64). Psoriasis vs. Healthy controls was evaluated on Inter-atrial electromechanical delay (p=0.002). Psoriasis was associated with significantly prolonged inter-atrial electromechanical delay compared with healthy controls (28 ± 7 ms vs. 23 ± 7 ms, P=0.002) and increased P-wave dispersion.
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