Key result
Psoriasis is linked to prolonged P-wave dispersion and a ~7% rate of abnormal ECGs.
Why the study?
Does psoriasis increase P-wave dispersion (a marker for atrial arrhythmias) compared to controls?
Case-Control (n=99)
Does psoriasis increase P-wave dispersion (a marker for atrial arrhythmias) compared to controls?
Absolute Event Rate: 7% vs 0%
Patients with psoriasis exhibit prolonged P-wave dispersion, indicating a potential increased risk for developing atrial fibrillation.
Psoriasis may warrant arrhythmia surveillance; leaves open whether PWD predicts AF events or alters management in observational cohorts.
BACKGROUND find out the presence of prolonged P-Wave Dispersion (PWD) on surface 12-lead electrocardiography and to assess the risk rhythm abnormalities in South Indian patients with psoriasis. AND METHODS was a prospective, cross-sectional, case control study. 49 psoriasis patients and 50 controls underwent relevant investigations 12-lead surface electrocardiography. PWD was calculated in the two groups and the degree of its prolongation was . Severity of psoriasis measured as PASI score was also correlated with PWD. duration of the disease was 7.88 years with a mean PASI score of 7.19. Patients with psoriasis had higher triglyceride as compared with controls, 7% of the patients had abnormal ECGs and none among the controls. Statistically, significant in PWD was observed in the two groups. No correlation between the PASI score and PWD could be established. of PWD is a reliable noninvasive and easily measurable marker of risk of development of AF in chronic inflammatory like psoriasis.
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Betdur et al. (2016) conducted a case-control in Psoriasis (n=99). Psoriasis vs. Controls without psoriasis was evaluated on Prolonged P-Wave Dispersion (PWD) and abnormal ECGs. Psoriasis was associated with a statistically significant prolongation of P-wave dispersion and a higher rate of abnormal ECGs (7% vs 0%) compared to controls.
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