Key result
Post-transplant EMB is linked to iatrogenic tricuspid damage, leaving ~62% with moderate-to-severe TR.
Why the study?
What is the prevalence of endomyocardial biopsy-related tricuspid apparatus damage and its impact on tricuspid regurgitation in heart transplant recipients?
Population
39 patients who received orthotopic heart transplantation between July 1987 and March 2005 and had adequate…
Design
Cohort
Follow-up
42.9+/-26.7 months
Authors
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May warrant closer TR surveillance after repeated biopsies in transplant recipients; leaves open whether noninvasive alternatives reduce iatrogenic damage.
Cohort (n=39)
No
What is the prevalence of endomyocardial biopsy-related tricuspid apparatus damage and its impact on tricuspid regurgitation in heart transplant recipients?
Endomyocardial biopsy after heart transplantation is associated with a high prevalence of iatrogenic tricuspid apparatus damage, which significantly contributes to the progression of tricuspid regurgitation.
Lo et al. (2007) conducted a cohort in Orthotopic heart transplantation (n=39). Endomyocardial biopsy was evaluated on Prevalence of tricuspid regurgitation and iatrogenic damage of tricuspid apparatus. Endomyocardial biopsy following heart transplantation was associated with a high prevalence of iatrogenic tricuspid apparatus damage, with 61.5% of patients having moderate or severe TR at follow-up.
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