Key result
Higher CRP-albumin ratio is linked to ~10-fold greater odds of high thrombus burden in STEMI.
Why the study?
Intracoronary thrombus burden strongly predicts adverse events in STEMI undergoing pPCI, and the CRP-serum albumin ratio is linked to thrombogenicity, but its relationship with coronary thrombus burden remained to be investigated.
Does a high CRP-albumin ratio predict high thrombus burden in patients undergoing primary PCI for newly diagnosed STEMI?
Population
216 patients undergoing pPCI due to STEMI
Comparison
Low thrombus burden (n = 120) vs high thrombus burden (n = 96)
Design
Retrospective study
Authors
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May aid thrombus risk stratification in STEMI; leaves open whether CRP-albumin ratio improves PCI outcomes or warrants intervention.
Observational (n=216)
Does a high CRP-albumin ratio predict high thrombus burden in patients undergoing primary PCI for newly diagnosed STEMI?
Odds Ratio: 10.206 (95% CI 2.987–34.872)
p-value: p=<.001
The CRP-albumin ratio is an independent predictor of high angiographic thrombus burden in patients undergoing primary PCI for STEMI.
Kaplangöray et al. (2023) conducted an observational in ST-segment elevation myocardial infarction (STEMI) (n=216). C-reactive protein-serum albumin ratio (CAR) was evaluated on High thrombus burden (HTB) (OR 10.206, 95% CI 2.987-34.872, p=<.001). The C-reactive protein-serum albumin ratio was an independent risk factor for high thrombus burden in patients with newly diagnosed STEMI (OR 10.206; 95% CI 2.987-34.872; P<0.001).
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