Key result
Review outlines current practices and unresolved issues in managing prosthetic valve dysfunction and thrombotic obstruction.
This review summarizes current practices and controversies in the diagnosis and management of prosthetic valve dysfunction, including anticoagulation, thrombolysis, and surgical interventions.
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Current practices for prosthetic valve dysfunction remain unsettled; leaves open optimal anticoagulation and thrombolysis strategies.
Immediate and long-term prognosis of patients with prosthetic valves critically depends on prevention, rapid diagnosis, and optimal treatment of complications. This review describes the current practice in management of prosthetic dysfunction and discusses unresolved or controversial issues such as: what is the optimal anticoagulation regimen in both mechanical and bioprosthetic heart valves? Is thrombolysis superior to surgery in thrombotic valve obstruction? Is valve replacement superior to conservative therapy for prosthetic valve endocarditis? In addition, recently obtained data relating to the incidence of early and late mortality, thromboembolism, anticoagulation-related hemorrhage, valve thrombosis, hemolysis, paravalvular leakage, and the necessity and risk of reoperation are presented.
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Binder et al. (1996) conducted a review in Prosthetic valve dysfunction. This review discusses current practices and unresolved issues in the management of prosthetic valve dysfunction, including anticoagulation regimens and treatment of thrombotic obstruction.
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