Key result
DDD pacing reduces exercise-induced ANF release vs rate-matched ventricular pacing.
Why the study?
Does DDD mode pacing reduce ANF release compared to rate matched ventricular pacing during exercise in patients with AV block?
Population
9 patients with permanent second or third degree AV block with implanted dual chamber pacemakers
Comparison
DDD mode pacing during exercise vs Rate matched ventricular pacing during exercise
Design
Other
Follow-up
at least 1 month after implantation
Authors
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Supports AV synchrony preservation during exercise in AV block; hypothesis-generating for hemodynamic effects, pending outcome trials.
Does DDD mode pacing reduce ANF release compared to rate matched ventricular pacing during exercise in patients with AV block?
Preservation of AV synchrony with DDD pacing reduces ANF release induced by heart rate acceleration during exercise compared to ventricular pacing.
Blanc et al. (1992) studied Permanent second or third degree AV block (n=9). DDD pacing vs. Rate matched ventricular pacing (VVT mode) was evaluated on Atrial natriuretic factor (ANF) levels and release. DDD pacing reduced atrial natriuretic factor release induced by heart rate acceleration during exercise compared to rate matched ventricular pacing.
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