Key result
Plasma aldosterone levels are ~52% higher in eccentric versus concentric LVH.
Why the study?
Is plasma aldosterone concentration associated with left ventricular geometry and diastolic function in treated essential hypertension?
Cross-Sectional (n=92)
No
Is plasma aldosterone concentration associated with left ventricular geometry and diastolic function in treated essential hypertension?
Absolute Event Rate: 15.2% vs 10%
p-value: p=<0.01
Higher plasma aldosterone concentrations are associated with eccentric left ventricular hypertrophy and impaired diastolic function in patients with treated essential hypertension.
No takes yet. Share an insight, caveat, or question.
No practice change indicated in treated hypertension; leaves open aldosterone's role in eccentric LV geometry.
Iwashima et al. (2002) conducted a cross-sectional in Essential hypertension (n=92). Eccentric left ventricular hypertrophy vs. Concentric left ventricular hypertrophy was evaluated on Plasma aldosterone concentration (ng/dl) (p=<0.01). Plasma aldosterone concentration was significantly higher in patients with eccentric left ventricular hypertrophy compared to those with concentric hypertrophy (15.2 vs. 10.0 ng/dl, p<0.01).
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