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January 19, 2019HeartOpen Access

Ethnic differences in atrial fibrillation in patients with heart failure from Asia-Pacific

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Key result

The prevalence of atrial fibrillation was markedly lower in Singapore-Asian patients with heart failure compared to NZ-Europeans (24% vs 63%; p<0.001).

Why the study?

Ethnic differences in the prevalence of atrial fibrillation in heart failure remain unclear.

Does the prevalence and clinical correlates of atrial fibrillation differ between Asian and New Zealand-European patients with heart failure?

Population

1746 patients with validated HF across Singapore and New Zealand

Comparison

Different ethnicities (Singapore-Asians vs NZ-Europeans)

Design

Prospective observational study

Follow-up

2 years

Authors

ETEugene S.J. TanNational University of SingaporeWTWan Ting TayHeart Failure & TransplantTTTiew‐Hwa Katherine TengHeart Failure & Transplant

Discussion

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Implication

Ethnic differences in AF prevalence among HF patients may affect screening and risk assessment; this cohort study leaves open mechanisms and generalizability.

Study Design

Type

Observational (n=1,746)

Multicenter

Yes

Structured PICO

Does the prevalence and clinical correlates of atrial fibrillation differ between Asian and New Zealand-European patients with heart failure?

P
Population
1,746 patients with validated heart failure (mean age 66 years, 26% women) prospectively studied across Singapore and New Zealand.
O
Outcome
Prevalence of atrial fibrillation (AF) and its clinical correlatescomposite

Main Result

Absolute Event Rate: 24% vs 63%

p-value: p=<0.001

There is a strikingly lower prevalence of atrial fibrillation among Asian compared with New Zealand-European patients with heart failure, with differing clinical correlates such as diabetes.

Cite This Study

Tan et al. (2019) conducted an observational in Heart failure (n=1,746). Asian ethnicity vs. NZ-European ethnicity was evaluated on Prevalence of atrial fibrillation (p=<0.001). The prevalence of atrial fibrillation was markedly lower in Singapore-Asian patients with heart failure compared to NZ-Europeans (24% vs 63%; p<0.001).

synapsesocial.com/papers/6aa23f25a80d56b6a327c341https://doi.org/10.1136/heartjnl-2018-314077

Topics

HFrEF treatmentHeart failureAtrial fibrillationPersistent AF managementAnticoagulation in AF
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