What does this research mean for the field?

Fibrillar haemostatic agents used during thoracic surgery can induce foreign-body reactions that mimic malignant nodal recurrence on PET-CT, often requiring tissue biopsy for definitive diagnosis due to overlapping imaging characteristics. Novelty: ClaimNovelty.INCREMENTAL. Consensus alignment: ConsensusAlignment.NEUTRAL.

What question did this study set out to answer?

To evaluate how retained fibrillar haemostatic agents mimic lymph node recurrence on post-operative surveillance imaging following thoracic cancer surgery.

September 10, 2026Interdisciplinary CardioVascular and Thoracic SurgeryOpen Access

Fibrillar haemostatic agents mimicking nodal recurrence after thoracic surgery: a cohort study

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Authors

TRThomas Roberts GRGiulia Raffaele KBKunal Bhakhri

Discussion

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Overview

Cohort study reveals fibrillar haemostats frequently mimic nodal recurrence on imaging after thoracic surgery, highlighting the need for surgical correlation to prevent unnecessary interventions.

Key Points

To evaluate how retained fibrillar haemostatic agents mimic lymph node recurrence on post-operative surveillance imaging following thoracic cancer surgery.
Retrospective cohort study evaluating 11 patients who underwent thoracic surgery for lung or mediastinal malignancy using intraoperative fibrillar haemostatic material and later developed suspicious imaging findings.
Analyzed follow-up CT and PET-CT imaging characteristics, fluorodeoxyglucose (FDG) uptake, maximum standardized uptake value (SUVmax), and subsequent histopathological outcomes.
Suspicious lesions were detected at a mean of 9.7 months (range 2–24) after surgery at or adjacent to prior fibrillar placement sites.
PET-CT detected increased FDG uptake in 7 of 9 evaluated cases with SUVmax ranging from 2.0 to 14.4, showing substantial overlap between benign and malignant lesions.
Active intervention was required in 10 of 11 patients (90.9%), with histopathology confirming benign foreign-body reactions in 7, malignant recurrence in 2, and both simultaneously in 2.

Cite This Study

Roberts et al. (2026) studied this question.

synapsesocial.com/papers/6aa27bbd58559d80afc752b2 https://doi.org/10.1093/icvts/ivag245

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September 10, 2026Interdisciplinary CardioVascular and Thoracic SurgeryOpen Access

Fibrillar haemostatic agents mimicking nodal recurrence after thoracic surgery: a cohort study

View Full Paper

Ask AI

Bookmark

Authors

TRThomas Roberts GRGiulia Raffaele KBKunal Bhakhri

Discussion

Member takes

Overview

Cohort study reveals fibrillar haemostats frequently mimic nodal recurrence on imaging after thoracic surgery, highlighting the need for surgical correlation to prevent unnecessary interventions.

Key Points

To evaluate how retained fibrillar haemostatic agents mimic lymph node recurrence on post-operative surveillance imaging following thoracic cancer surgery.
Retrospective cohort study evaluating 11 patients who underwent thoracic surgery for lung or mediastinal malignancy using intraoperative fibrillar haemostatic material and later developed suspicious imaging findings.
Analyzed follow-up CT and PET-CT imaging characteristics, fluorodeoxyglucose (FDG) uptake, maximum standardized uptake value (SUVmax), and subsequent histopathological outcomes.
Suspicious lesions were detected at a mean of 9.7 months (range 2–24) after surgery at or adjacent to prior fibrillar placement sites.
PET-CT detected increased FDG uptake in 7 of 9 evaluated cases with SUVmax ranging from 2.0 to 14.4, showing substantial overlap between benign and malignant lesions.
Active intervention was required in 10 of 11 patients (90.9%), with histopathology confirming benign foreign-body reactions in 7, malignant recurrence in 2, and both simultaneously in 2.

Cite This Study

Roberts et al. (2026) studied this question.

synapsesocial.com/papers/6aa27bbd58559d80afc752b2 https://doi.org/10.1093/icvts/ivag245

View Full Paper

Ask AI

Bookmark