Key result
Lengthening the PQ interval shifts atrial contraction earlier in diastole and shortens slow ventricular filling.
Why the study?
How does variation in PQ interval affect patterns of atrioventricular valve motion and flow in patients with complete heart block and normal ventricular function?
Population
n=5 patients with complete heart block, normal ventricular function and an implanted dual chamber pacemaker
Comparison
Variation in programmable PQ intervals vs Different PQ intervals within the same patients
Design
Case_series
Authors
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Should not yet guide PQ programming; hypothesis-generating for diastolic effects in paced complete heart block.
How does variation in PQ interval affect patterns of atrioventricular valve motion and flow in patients with complete heart block and normal ventricular function?
Variation in the PQ interval alters the timing of AV valve motion and flow dynamics but does not affect overall ventricular and atrial dimensions in patients with normal ventricular function.
Freedman et al. (1986) studied Complete heart block with normal ventricular function (n=5). Variation in programmable PQ interval was evaluated on Patterns of atrioventricular (AV) valve motion and flow. Lengthening the programmable PQ interval from 75 to 250 ms caused atrial contraction to occur progressively earlier in diastole and decreased the duration of mid-diastolic slow ventricular filling.
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