Key result
Delivery by caesarean section rapidly decreased serum adiponectin levels within 24 hours from a median of 8.34 mg/l to 6.81 mg/l (P<0.001).
Why the study?
Does delivery via caesarean section alter circulating adiponectin levels in pregnant women?
Cohort (n=43)
Does delivery via caesarean section alter circulating adiponectin levels in pregnant women?
Effect estimate: relative decrease to 83% of pregnant values
Absolute Event Rate: 6.81% vs 8.34%
p-value: p=<0.001
Circulating adiponectin levels decrease rapidly within 24 to 48 hours after delivery, with the most pronounced changes in the high-molecular weight subfraction.
Caesarean delivery-associated adiponectin drop should not change practice; hypothesis-generating for postpartum metabolic risk.
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Fuglsang et al. (2010) conducted a cohort in Pregnancy (n=43). Delivery by caesarean section vs. Pre-delivery (fasting state) was evaluated on Serum adiponectin levels (relative decrease to 83% of pregnant values, p=<0.001). Delivery by caesarean section rapidly decreased serum adiponectin levels within 24 hours from a median of 8.34 mg/l to 6.81 mg/l (P<0.001).
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