Key result
Real-time 3D color flow Doppler quantification of mitral inflow and LVOT outflow stroke volumes correlated highly with sonomicrometry (R = 0.96) and showed smaller bias than 2D TTE.
Why the study?
Does real-time 3D color flow Doppler TTE accurately quantify mitral inflow and aortic outflow stroke volumes compared to sonomicrometry in an open-chest pig model?
Population
5 open-chest pigs evaluated across 46 different hemodynamic states
Comparison
Real-time 3-dimensional color flow Doppler… vs 2-dimensional TTE and left ventricular…
Design
Preclinical
Authors
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Preclinical validation of 3D Doppler flow quantification supports further development; leaves open translation to human echocardiography.
Does real-time 3D color flow Doppler TTE accurately quantify mitral inflow and aortic outflow stroke volumes compared to sonomicrometry in an open-chest pig model?
Effect estimate: R = 0.96
Real-time 3D color flow Doppler TTE provides accurate quantification of mitral and aortic stroke volumes, outperforming conventional 2D TTE in an animal model.
Shimada et al. (2014) studied Hemodynamic states in open-chest animal model (n=5). Real-time 3-dimensional (3D) color flow Doppler method vs. 2-dimensional (2D) TTE and LV sonomicrometry was evaluated on Accuracy of mitral inflow and LVOT outflow stroke volumes compared to sonomicrometry (R = 0.96). Real-time 3D color flow Doppler quantification of mitral inflow and LVOT outflow stroke volumes correlated highly with sonomicrometry (R = 0.96) and showed smaller bias than 2D TTE.
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