Key result
On-pump beating-heart coronary artery bypass grafting showed no significant difference in early mortality compared to arrested-heart surgery (17.9% vs 28.6%, p=0.53).
Why the study?
To evaluate the on-pump beating-heart technique for coronary artery bypass in patients with acute myocardial infarction and left main disease, comparing early postoperative results with conventional on-pump arrested-heart surgery.
Does on-pump beating-heart coronary artery bypass grafting improve early postoperative mortality compared to on-pump arrested-heart surgery in patients with acute myocardial infarction and left main disease?
Cohort (n=85)
No
Does on-pump beating-heart coronary artery bypass grafting improve early postoperative mortality compared to on-pump arrested-heart surgery in patients with acute myocardial infarction and left main disease?
Absolute Event Rate: 17.9% vs 28.6%
p-value: p=0.53
In patients with acute myocardial infarction and left main disease undergoing emergency surgery, on-pump beating-heart CABG reduces myocardial injury markers but does not significantly improve early mortality compared to arrested-heart surgery.
BACKGROUND: The aims of this study were to evaluate the on-pump beating-heart technique of coronary artery bypass in patients with acute myocardial infarction and left main disease, and to retrospectively compare the early postoperative results with those of conventional on-pump arrested-heart coronary surgery. METHODS: Eighty-five patients with acute myocardial infarction caused by left main disease, who underwent emergency surgery between January 1998 and April 2017 at Saiseikai Utsunomiya Hospital, were enrolled in this study. Of these patients, 56 were evaluated using propensity-matched analysis. The patients were divided into two groups according to the surgical procedure: group A ( n = 28) had on-pump surgery on the arrested heart, and group B ( n = 28) had on-pump surgery on the beating heart. Early postoperative results were compared between the two groups. RESULTS: , p = 0.01). The early mortality rate was higher in group A than group B, but the difference was not significant (group A 28.6% vs. group B 17.9%, p = 0.53). CONCLUSIONS: There was no significant advantage based on surgical procedure between on-pump beating-heart surgery and on-pump surgery on the arrested heart. On-pump beating-heart coronary artery bypass grafting significantly reduced the peak creatine kinase myocardial band level, but there were no significant differences in the early postoperative data, including the mortality rate and left ventricular function.
No takes yet. Share an insight, caveat, or question.
Tsutsumi et al. (2019) conducted a cohort in Acute myocardial infarction and left main disease (n=85). On-pump beating-heart coronary artery bypass vs. On-pump arrested-heart coronary surgery was evaluated on Early mortality rate (p=0.53). On-pump beating-heart coronary artery bypass grafting showed no significant difference in early mortality compared to arrested-heart surgery (17.9% vs 28.6%, p=0.53).
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: