Key result
Sub-Saharan Black patients exhibited a significantly worse cardiovascular and renal risk profile, including a higher prevalence of eGFR <60 ml/min/1.73 m2 (26.2% vs 7.7%), compared to European White patients despite being younger.
Why the study?
Greater vulnerability of Black versus White individuals to cardiovascular disease and chronic kidney disease is established in the United States, but studies involving sub-Saharan Blacks are scarce.
Do sub-Saharan Black patients have a higher risk of cardiovascular disease and chronic kidney disease compared to European White patients?
Population
168 sub-Saharan Blacks and 93 European Whites in an ongoing clinical trial
Comparison
Sub-Saharan Blacks vs European Whites
Design
Baseline cross-sectional analysis of clinical trial data
Authors
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Warrants earlier CKD screening in sub-Saharan Black patients; leaves open whether ethnicity-specific thresholds improve outcomes in prospective studies.
Cross-Sectional (n=261)
Yes
Do sub-Saharan Black patients have a higher risk of cardiovascular disease and chronic kidney disease compared to European White patients?
Absolute Event Rate: 26.2% vs 7.7%
p-value: p=<0.0001
Sub-Saharan Black patients exhibit a significantly worse cardiovascular and kidney disease risk profile at a younger age compared to European White patients, highlighting the need for targeted health policies.
Yu et al. (2024) conducted a cross-sectional in High risk for cardiovascular disease and chronic kidney disease (n=261). Sub-Saharan Black race vs. European White race was evaluated on eGFR <60 ml/min/1.73 m2 (p=<0.0001). Sub-Saharan Black patients exhibited a significantly worse cardiovascular and renal risk profile, including a higher prevalence of eGFR <60 ml/min/1.73 m2 (26.2% vs 7.7%), compared to European White patients despite being younger.
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