Key result
A statistical model based on defibrillation efficacy curves from over 1,500 implants was derived to establish an implant criterion meeting predetermined targets for successful defibrillation.
Population
Data from over 1,500 defibrillator implants, including successful epicardial and transvenous electrode…
Design
Other
Authors
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May support modeling-based defibrillator implant criteria; leaves open prospective validation before clinical adoption.
A statistical model based on defibrillation efficacy curves can be used to establish evidence-based defibrillator implant criteria, potentially replacing empirical safety margins.
DeGroot et al. (1997) studied Cardioverter defibrillator implantation (n=1,500). Statistically derived defibrillator implant criterion vs. Empirical criteria (2:1 energy safety margin or fixed 10 joules) was evaluated on Probability of successful defibrillation. A statistical model based on defibrillation efficacy curves from over 1,500 implants was derived to establish an implant criterion meeting predetermined targets for successful defibrillation.
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