Key result
Diabetic microangiopathy is associated with ~53% higher plasma β-TG levels compared to uncomplicated diabetes.
Population
145 subjects including 35 healthy controls, 25 non-diabetic patients with ischemic heart disease, and 85…
Design
Cross-sectional
Authors
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β-TG elevation associates with diabetic microangiopathy; hypothesis-generating and should not yet change practice.
Cross-Sectional (n=145)
No
Absolute Event Rate: 35.8% vs 23.4%
p-value: p=<0.005
Elevated plasma β-thromboglobulin levels in diabetic patients with microangiopathy suggest in vivo platelet hyperfunction, which may contribute to vascular complications.
Yamada et al. (1980) conducted a cross-sectional in Diabetes mellitus and ischemic heart disease (n=145). Diabetic microangiopathy (e.g., proteinuria) vs. Diabetics without microangiopathy, non-diabetic IHD patients, and healthy controls was evaluated on Plasma β-thromboglobulin (β-TG) levels (p=<0.005). Plasma β-thromboglobulin levels were significantly higher in diabetic patients compared to controls, and particularly elevated in diabetics with microangiopathy (e.g., 35.8 ng/ml with proteinuria vs 23.4 ng/ml without, p<0.005).
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