Key result
Propofol (1 mg/kg) resulted in lesser haemodynamic changes, including no significant change in afterload, compared with thiopentone (2 mg/kg) during electroconvulsive therapy.
Why the study?
Does propofol improve haemodynamic stability compared to thiopentone in patients undergoing electroconvulsive therapy?
Population
28 ASA 1 or 2 patients scheduled for electroconvulsive therapy (ECT)
Comparison
Propofol 1 mg/kg administered prior to bilateral… vs Thiopentone 2 mg/kg administered prior to…
Design
RCT, randomly divided into two groups
Follow-up
until ten minutes after the seizure
Authors
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Propofol may be preferred over thiopentone to limit haemodynamic changes in ECT; extends RCT evidence guiding anaesthetic selection.
RCT (n=28)
randomly divided
Does propofol improve haemodynamic stability compared to thiopentone in patients undergoing electroconvulsive therapy?
p-value: p=<0.05
Propofol anaesthesia results in lesser haemodynamic changes and afterload increases compared to thiopentone during electroconvulsive therapy.
Kadoi et al. (2003) conducted an RCT in Electroconvulsive therapy (n=28). Propofol vs. Thiopentone 2 mg/kg was evaluated on Haemodynamics and cardiac function during ECT (p=<0.05). Propofol (1 mg/kg) resulted in lesser haemodynamic changes, including no significant change in afterload, compared with thiopentone (2 mg/kg) during electroconvulsive therapy.
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