Key result
The transition from trivalent to bivalent oral polio vaccine led to a dramatic increase in circulating vaccine-derived poliovirus cases, paralyzing over 3300 children in 43 countries.
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The transition from trivalent to bivalent oral polio vaccine inadvertently led to a massive increase in vaccine-derived poliovirus cases, highlighting the critical need for the inactivated polio vaccine in eradication efforts.
Chumakov et al. (2025) conducted an editorial in Polio. Transition from trivalent to bivalent oral polio vaccine was evaluated on Circulating vaccine-derived poliovirus (cVDPV) cases. The transition from trivalent to bivalent oral polio vaccine led to a dramatic increase in circulating vaccine-derived poliovirus cases, paralyzing over 3300 children in 43 countries.
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