Key result
12-week cardiac rehab linked to improved endothelium-related myocardial blood flow in HF.
Why the study?
Does cardiac rehabilitation improve coronary endothelial function in patients with heart failure due to non-ischaemic dilated cardiomyopathy?
Population
n=29 clinically stable heart failure patients with non-ischaemic dilated cardiomyopathy and without coronary…
Comparison
12 weeks of cardiac rehabilitation and… vs Baseline (before intervention)
Design
Cohort
Follow-up
12 weeks
Authors
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Cardiac rehabilitation may enhance coronary vasomotion in non-ischaemic HF; leaves open clinical outcome benefits pending randomized confirmation.
Cohort (n=29)
Does cardiac rehabilitation improve coronary endothelial function in patients with heart failure due to non-ischaemic dilated cardiomyopathy?
Absolute Event Rate: 0.19% vs -0.03%
p-value: p=<0.001
Cardiac rehabilitation significantly improves coronary vasomotion and endothelial function in patients with heart failure due to non-ischaemic dilated cardiomyopathy.
Legallois et al. (2014) conducted a cohort in Heart failure due to non-ischaemic dilated cardiomyopathy (n=29). Cardiac rehabilitation vs. Baseline was evaluated on Endothelium-related change in myocardial blood flow from rest to cold pressor test (mL/min/g) (p=<0.001). 12 weeks of cardiac rehabilitation significantly improved endothelium-related change in myocardial blood flow from -0.03 to 0.19 mL/min/g (p<0.001) in patients with heart failure.
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