Key result
Miconazole administration in seven patients with hematologic malignancies resulted in eight episodes of major adverse cardiorespiratory and anaphylactic reactions after the first dose.
Population
7 patients with hematologic malignancies and suspected or proven fungal infections, with no history of…
Design
Case_series
Authors
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Supports first-dose vigilance with miconazole in hematologic malignancies; leaves open incidence and generalizability.
Case Report (n=7)
Miconazole administration can cause severe, reversible cardiorespiratory and anaphylactic reactions after the first dose, necessitating careful monitoring of dose and administration rate.
Fainstein et al. (1980) conducted a case report in Hematologic malignancies with suspected or proven fungal infections (n=7). Miconazole was evaluated on Major adverse cardiorespiratory and anaphylactic reactions. Miconazole administration in seven patients with hematologic malignancies resulted in eight episodes of major adverse cardiorespiratory and anaphylactic reactions after the first dose.
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