Key result
Irregular plaque geometries produce the highest carotid wall shear stress in 2D computational models.
Population
2D computational models of stenosed carotid arteries using computational fluid dynamics for a Non-Newtonian…
Comparison
Different plaque geometries vs Comparison among different plaque geometries and…
Design
Preclinical
Authors
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May prompt refined CFD models of carotid stenosis; leaves open any clinical relevance pending in vivo validation.
Computational modeling demonstrates that irregular plaque geometries in stenosed carotid arteries generate the highest wall shear stress.
Bhatia et al. (2016) studied Atherosclerosis in stenosed carotid arteries. Different shapes of plaque (smooth, irregular, cosine, blood clot) vs. Healthy wall / other plaque shapes was evaluated on Wall shear stress (WSS). Irregular plaque geometries cause the highest wall shear stress in the common carotid artery compared to smooth, cosine, or blood clot geometries in a 2D computational fluid dynamics model.
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