Key result
The lowest pulmonary artery pulsatility index quartile was associated with a 60% greater risk of all-cause mortality compared with the highest quartile (HR 1.60; 95% CI 1.36-1.88; P<0.001).
Why the study?
Whether pulmonary artery pulsatility index (PAPi) is associated with adverse outcomes across a heterogeneous population was unknown.
Does a lower pulmonary artery pulsatility index (PAPi) predict all-cause mortality, major adverse cardiac events, and heart failure hospitalizations in patients undergoing right heart catheterization?
Cohort (n=8,285)
Does a lower pulmonary artery pulsatility index (PAPi) predict all-cause mortality, major adverse cardiac events, and heart failure hospitalizations in patients undergoing right heart catheterization?
Hazard Ratio: 1.6 (95% CI 1.36–1.88)
p-value: p=<0.001
A low pulmonary artery pulsatility index (PAPi) is a strong predictor of all-cause mortality, major adverse cardiac events, and heart failure hospitalizations across a broad spectrum of patients undergoing right heart catheterization.
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Low PAPi signals higher mortality, MACE, and HF hospitalization risk across broad CVD; extends prior observations but leaves open prospective validation before practice change.
A 2022 study conducted a cohort in Undergoing right heart catheterization (n=8,285). Lowest pulmonary artery pulsatility index (PAPi) quartile vs. Highest PAPi quartile was evaluated on All-cause mortality (HR 1.60, 95% CI 1.36-1.88, p=<0.001). The lowest pulmonary artery pulsatility index quartile was associated with a 60% greater risk of all-cause mortality compared with the highest quartile (HR 1.60; 95% CI 1.36-1.88; P<0.001).
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