Synthetic access to α-substituted prop-2-ynylamines and α-acetylenic amino acids via the t-butyl N-trimethylsilylprop-2-ynylcarbamate dianion

The dianion derived from t-butyl N-trimethyl-silylprop-2-ynycarbamate undergoes alkylation and carboxylation at the propynylic position, leading to derivatives of acetylenic amines and amino acids.