Why the study?
The relationship between estimated glomerular filtration rate and para-perirenal fat thickness compared with other indices of adiposity in type 2 diabetes mellitus required investigation.
Population
337 patients with T2DM
Comparison
Para-perirenal fat thickness vs other obesity-related indicators
Design
Single-center, retrospective and cross-sectional study
Key result
Para-perirenal fat thickness was the strongest predictor of chronic kidney disease among obesity-related indicators in patients with type 2 diabetes mellitus (AUC 0.686).
Authors
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Para-perirenal fat thickness may refine CKD risk assessment in T2DM; leaves open prospective validation and incremental value over standard markers.
Cross-Sectional (n=337)
No
Effect estimate: AUC 0.686 (95% CI 0.582-0.791)
p-value: p=0.001
Para-perirenal fat thickness is a stronger predictor of reduced eGFR and chronic kidney disease than other traditional obesity-related indicators in patients with type 2 diabetes.
Xu et al. (2023) conducted a cross-sectional in Type 2 diabetes mellitus (n=337). Para-perirenal fat thickness (PRFT) vs. Other obesity-related indicators (BMI, WC, WHR, TAF, SAT, VAT) was evaluated on Prediction of chronic kidney disease (CKD) (AUC 0.686, 95% CI 0.582-0.791, p=0.001). Para-perirenal fat thickness was the strongest predictor of chronic kidney disease among obesity-related indicators in patients with type 2 diabetes mellitus (AUC 0.686).