Why the study?
Pararenal fat accumulation is considered a risk factor for CKD, but its association with renal dysfunction in patients without clinically significant cardiovascular disease required investigation.
Population
320 patients without clinically significant CVDs (mean age 63.8 ± 13.9 years)
Comparison
Pararenal fat tissue thickness assessed across body weight categories and CKD stages
Design
Cross-sectional study
Key result
Pararenal fat tissue thickness was significantly associated with the risk of developing renal dysfunction (OR 6.198; 95% CI 1.958-19.617; p<0.05) in patients without significant cardiovascular disease.
Authors
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Pararenal fat thickness may flag early renal risk in non-CVD patients; hypothesis-generating and requires prospective validation before clinical use.
Cross-Sectional (n=320)
Odds Ratio: 6.198 (95% CI 1.958–19.617)
p-value: p=< 0.05
Increased pararenal fat tissue thickness is significantly associated with reduced glomerular filtration rate and a higher risk of renal dysfunction in patients without clinical cardiovascular disease.
Брагина et al. (2022) conducted a cross-sectional in Patients without clinically significant cardiovascular diseases (n=320). Pararenal fat tissue (PRFT) thickness was evaluated on Renal dysfunction development (OR 6.198, 95% CI 1.958-19.617, p=< 0.05). Pararenal fat tissue thickness was significantly associated with the risk of developing renal dysfunction (OR 6.198; 95% CI 1.958-19.617; p<0.05) in patients without significant cardiovascular disease.