Key result
Arteriovenous diffusive oxygen shunting proves negligible in resting and working muscles of dogs and rats.
Authors
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Negligible shunting supports simplified muscle oxygen transport models; leaves open human translation and exercise relevance.
Honig et al. (1991) studied this question. Arteriovenous oxygen diffusion was evaluated on Distribution of O2 within and among arterioles and venules. Arteriovenous diffusive oxygen shunting in resting and working gracilis muscles of dogs and rats was found to be negligible, with effluent PO2 closely approximating mean end-capillary PO2.
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