Key result
Theoretical simulations of oxygen transport in skeletal muscle indicate that diffusive oxygen loss from arterioles equals about 85% of consumption, with capillaries absorbing much of this oxygen.
Population
Simulated three-dimensional configuration of capillaries and arterioles in a cuboidal tissue region, based…
Design
Preclinical
Authors
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Refines skeletal muscle oxygenation models; leaves open arteriolar oxygen's role in metabolic flow regulation.
Diffusive exchange between arterioles and capillaries plays an important role in distributing oxygen throughout skeletal muscle tissue, supporting the hypothesis that arteriolar oxygen content participates in metabolic regulation of blood flow.
Secomb et al. (1994) studied Oxygen transport in skeletal muscle. Theoretical simulations of oxygen transport was evaluated on Diffusive oxygen exchange between arterioles and capillaries. Theoretical simulations of oxygen transport in skeletal muscle indicate that diffusive oxygen loss from arterioles equals about 85% of consumption, with capillaries absorbing much of this oxygen.
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