What is the clinical evidence from this study?

Study design: Other. Intervention: Oxygen permeability assumption. Primary outcome: Oxygen flux and permeability.

What does this research mean for the field?

The permeability to oxygen of blood-perfused tissue is an order of magnitude higher than previously assumed based on unperfused tissue measurements. Novelty: ClaimNovelty.CONTRADICTORY. Consensus alignment: ConsensusAlignment.CHALLENGES_CONSENSUS.

March 1, 1989AJP Heart and Circulatory Physiology

Rate of oxygen loss from arterioles is an order of magnitude higher than expected

View Full Paper

Ask AI

Bookmark

Key result

Hamster model suggests blood-perfused tissue oxygen permeability is ~10-fold higher than previously assumed.

Authors

APAleksander S. PopelJohns Hopkins University RPRoland N. PittmanVirginia Commonwealth University Medical Center MEMary L. EllsworthWestern University

Discussion

Member takes

Implication

May necessitate revising tissue oxygen transport models; leaves open validation in human microcirculation.

PICO

Exposure / Comparator

Oxygen permeability assumption

Primary Outcome

Oxygen flux and permeability

Cite This Study

Popel et al. (1989) studied this question. Oxygen permeability assumption was evaluated on Oxygen flux and permeability. Analysis of oxygen flux from arterioles in the hamster cheek pouch retractor muscle indicated that permeability to oxygen of blood-perfused tissue may be an order of magnitude higher than assumed.

synapsesocial.com/papers/6aa5c2612e0c4dc4f87f2ede https://doi.org/10.1152/ajpheart.1989.256.3.h921

View Full Paper

Ask AI

Bookmark

Rate of oxygen loss from arterioles is an order of magnitude higher than expected

Discussion

Member takes

Implication

PICO

Cite This Study

Rate of oxygen loss from arterioles is an order of magnitude higher than expected

Discussion

Member takes

Implication

PICO

Cite This Study

Also Consider

Also Consider